NEXO

NEXO is a daily medical diagnosis game for medical students, residents, and physicians who want to practice clinical reasoning in short, focused sessions. Available on the web and iPhone, it combines fictional clinical cases, progressive clues, and structured diagnostic feedback in six languages. A new case. Six clues. Your diagnosis. Each case begins with limited information. As you reveal up to six progressive clues, you consider possible diagnoses, interpret clinical findings, and refine your hypothesis. Submit your answer through the ICD classification and discover how close it is to the correct diagnosis. NEXO’s distinctive feature is its five levels of diagnostic proximity: exact match, same subcategory, same group, same chapter, or distant. This feedback locates your answer within the classification hierarchy, giving you a more specific way to understand an incorrect attempt. The challenge is to reach the diagnosis with as few clues as possible. THREE WAYS TO PRACTICE Daily Challenge Solve the same daily case as players around the world. Build a regular practice habit, compare results with colleagues, and explore different areas of medicine through sessions designed to fit into approximately five minutes. Continents Explore cases organized around regional epidemiology across Africa, the Americas, Asia, Europe, and Oceania. Encounter presentations that expand your practice beyond the conditions most familiar in your local setting. Multimedia Combine clinical clues with images and auscultation. Cases include radiographs, CT and MRI scans, ultrasound, ECGs, dermatology images, histopathology, endoscopy, and cardiac and respiratory sounds. Practice connecting what you read with what you see and hear. A STRUCTURED FOUNDATION FOR EACH CASE NEXO Core is the platform’s structured medical knowledge base. It connects diseases, syndromes, clinical findings, investigations, differential diagnoses, and reference material. This network supports case auditing by checking whether the proposed diagnosis, clues, explanations, and related concepts are supported by the organized source material. NEXO publishes its educational methodology, references, and approach to clinical governance so users can examine how the platform is built. Its design draws on educational principles including retrieval practice, distributed practice, and learning from feedback. These principles inform the product’s design; they do not constitute proof of NEXO’s educational effectiveness, which requires independent evaluation. BUILT FOR A GLOBAL MEDICAL COMMUNITY NEXO is available in English, Portuguese, Spanish, French, German, and Russian. Play in your preferred language through a web browser or the iPhone app, with progress synchronized between platforms. The collection contains hundreds of cases spanning a broad range of medical specialties. Whether you are preparing for clinical rotations, revisiting familiar presentations, or exploring less common diagnoses, you can fit a case into a break between classes or study sessions. Practice also has a social dimension. Compare results through rankings, connect with friends, and participate in study groups. Earn achievements and sinapses, NEXO’s virtual currency, as you progress. START WITH A FREE DAILY CASE The daily case is free. Sinapses earned through play can unlock Continents and Multimedia experiences on any plan. Optional Pro and Max subscriptions provide additional practice access and benefits. A public demonstration lets you experience the case format before committing to a regular practice routine. NEXO is designed for education and uses fictional clinical scenarios. It complements medical study and supervised clinical training; it does not diagnose real patients or provide guidance for clinical decisions. Try NEXO at https://nexo.wiki.br and find out how many clues you need to reach the diagnosis.